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Stereocontrolled Generation of the (2 R ) Chroman Core of Vitamin E: Total Synthesis of (2 R ,4′ RS ,8′ RS )-α-Tocopherol

✍ Scribed by Hernández-Torres, Gloria; Urbano, Antonio; Carreño, M. Carmen; Colobert, Françoise


Book ID
119953081
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
485 KB
Volume
11
Category
Article
ISSN
1523-7060

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Studies on the Synthesis of (2R,4′R,8′R)
✍ Noal Cohen; John W. Scott; Fred T. Bizzaro; Rocco J. Lopresti; Wayne F. Eichel; 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 German ⚖ 523 KB

## Abstract As an extension of previous studies on the total synthesis of (2R,4′R,8′R)‐α‐tocopherol (**1**) [1] [2], (S)‐(−)‐2‐(6‐benzyloxy‐2,5,7,8‐tetramethylchroman)acetic acid (**6**), a pivotal intermediate, possessing the absolute configuration required for construction of **1** was prepared b