Synthesis of (24R)-3β-hydroxystigmast-5-en-7-one
✍ Scribed by N. V. Kovganko; Zh. N. Kashkan
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 279 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0009-3130
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📜 SIMILAR VOLUMES
Reaction of 36-benzyloxy-5-hydroxy-5a-cholestan-6-one (1) with potassium t-butoxide in t-butyl alcohol gives 5-hydroxy-56-cholest-3-en-6-one (2), which on direct irradiation (300 nm) ?-n hexanes gives the B-seco steroid 9 and the indenacetaldehyde derivative 10.
## Abstract A method has been described for the synthesis of tritiated [7‐^3^H]‐3β,16β‐dihydroxy‐5‐androsten‐17‐one of high specific activity starting from [7‐^3^H]‐5‐androsten‐17‐one. The identity of the radioactive steroid was established by thin layer chromato‐graphy, gas chromatography and gas