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Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship

✍ Scribed by Pritam Thapa; Radha Karki; Hoyoung Choi; Jae Hun Choi; Minho Yun; Byeong-Seon Jeong; Mi-Ja Jung; Jung Min Nam; Younghwa Na; Won-Jea Cho; Youngjoo Kwon; Eung-Seok Lee


Book ID
108072792
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
440 KB
Volume
18
Category
Article
ISSN
0968-0896

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ChemInform Abstract: Synthesis of 2,4-Di
✍ Eung-Seok Lee; et al. et al. 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

## Abstract Twentythree chromenopyridines, substituted at the 2‐ and 4‐position with 5‐or 6‐membered heteroaromatics, are synthesized by treatment of pyridinium iodide salts (III) with chromanones (IV) utilizing a modified Kroehnke synthesis.