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Synthesis, Topoisomerase I Inhibition and Structure—Activity Relationship Study of 2,4,6-Trisubstituted Pyridine Derivatives.

✍ Scribed by Yurngdong Jahng; Eung-Seok Lee; et al. et al.

Publisher
John Wiley and Sons
Year
2004
Weight
86 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract A variety of (het)aryl‐substituted benzoquinoline derivatives (III) (24 examples) is designed, synthesized and evaluated for their topoisomerase inhibitory activities and their cytotoxicity against several human cancer cell lines.