A one-pot synthesis of 6-deoxy-6-[18F]fluoro-L-ascorbic acid (18F-DFA) has been developed via nucleophilic displacement of a cyclic sulfate with no-carrier-added [18F]fluoride ion. Isolated radiochemical yields of around 15% were obtained with radiochemical purity of over 99% after overall synthesis
β¦ LIBER β¦
Synthesis of 18F-labeled 6- and 7-fluoropalmitic acids
β Scribed by M.S. Berridge; T.J. Tewson; M.J. Welch
- Publisher
- Elsevier Science
- Year
- 1983
- Weight
- 470 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0020-708X
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