✦ LIBER ✦

Synthesis of 15N,15N-imidazoleacetic acid

✍ Scribed by George D. Prell

Publisher: John Wiley and Sons
Year: 1991
Tongue: French
Weight: 301 KB
Volume: 29
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580290115

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✦ Synopsis

S u in ma r y

1sN.15N-imidazoleacetic acid was synthesized from 15N, lSN-DL-histidine (>99 atom % 15N). The latter. oxidized with sodium hypochlorite. formed 15N.15N-imidazoleacetoniuile. The free acid was prepared after acid hydrolysis of the nitrile, elution from an anion exchange column with acetic acid, then drying. Formation of by-product(s). produced when other methods were used, and which may conraminate some commercial sources of imidazoleacetic acid. was avoided with this method.

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