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Synthesis of 14C-labelled sodium pariprazole (E3810)

✍ Scribed by Katsuya Tagami; Shigeru Chiku; Shigeru Sohda

Publisher
John Wiley and Sons
Year
1993
Tongue
French
Weight
206 KB
Volume
33
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Sodium pariprazole (E3810), an inhibitory of H^+^,K^+^‐ATPase, was synthesized labelled with carbon‐14, starting from 2‐mercapto[2‐^14^C]‐benzimidazole 1 with a specific activity of 888 MBq/mmol. It was obtained in 49.3% radiochemical yield with a radiochemical purity of more than 98%.

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