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Synthesis of 14C-labelled 5-ethyl derivatives of pyrimidine

✍ Scribed by M. Skakun-Todorovič; V. Jezdič

Publisher
John Wiley and Sons
Year
1973
Tongue
French
Weight
270 KB
Volume
9
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

A method for the synthesis of 5‐ethylorotic acid‐2‐^14^C (V), 5‐ethyluracil‐2‐^14^C (VI) and 5‐ethylytosine‐2‐^14^C (VIII) starting from thiourea‐^14^C with the specific activity of 30 mCi/mM has been described. The labelled compounds obtained show satisfactory chemical and radiochemical purity. The method was modified and adapted for work at the level 1‐5 mM.

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