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Synthesis of 14C-labeled inosine 5′-phosphate

✍ Scribed by Shinji Sakata; Shiro Ikegami

Publisher
John Wiley and Sons
Year
1978
Tongue
French
Weight
172 KB
Volume
14
Category
Article
ISSN
0022-2135

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✦ Synopsis

I4C-Labeled inosine 5'-phosphate was synthesized by direct phosphorylation of i n 0 s i n e -8 -~~C with phosphoryl chloride followed by hydrolysis of the resulting phosphorodichloridate. Isolation and recrystallization o f its disodium salt afforded pure material in 66.8% overall chemical yield.

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