✍ Scribed by M. A. Muhs
No coin nor oath required. For personal study only.
Thp Wittig synthesis has been used to prepare conveniently carbon-14 labeled 1-olejh in the Cs to c 8 range in about 60 % yield. Thp chemicd and radiochemical purities of the products exceeded 99.5 %, The common source of carbon-14 in these reactions was methyl-14C-triphenylphosphonium iodide which was readily and quantitatively prepared j i o m commercially available methyl-14C iodide.
📜 SIMILAR VOLUMES
## Abstract The synthesis of radiolabelled 4‐hydroxy‐3‐(3‐methyl‐3‐buten‐1‐ynyl) benzaldehyde (eutypine 1), a phytotoxic compound isolated from the culture media of the fungus __Eutypa lata__, responsible for vineyard die‐back, is described. The radioisotope ^14^C was introduced __via__ a Wittig re
14C-labeled chlorogenic acid (specijic activity 30.6 nCilmg) was synthesized by reaction of diphenylmethyl-I-0-ethoxy-carbonyl- 4,5-0-isopropylidenequinate ( V ) with 0,O-dimethylcarbonyl caffeoyl chloride-u-14C (VIII) followed by selective hydrolysis of the protecting groups.
## Abstract A convenient synthesis of the strained methylene‐bridged __trans__‐cyclooctenes bicyclo[3.3.1]‐1 (2)‐nonene **(1)**, bicyclo[4.2.1]‐1(8)‐nonene **(2)**, and bicyclo[4.2.1]‐1(2)‐nonene **(3)** by the intramolecular __Wittig__ reaction is described (see __Schemes 1–4__). The (3‐oxocycloal
## Abstract Dimethoxymethyl phenobarbital (DMMP), labeled with ^14^C on the ring and side chains was prepared for drug metabolism studies. The synthesis of DMMP‐ethyl‐1–^14^C (4a) in four steps provided a 43% yield from ethyl‐1–^14^C iodide. The yields of DMMP‐2–^14^C (4b) and DMMP‐dimethylene‐^14^
## Abstract Phenylpropionitrile‐1‐^14^C was prepared by the reaction of potassium cyanide‐^14^C with phenethyl chloride. Conversion of the nitrile to methylphenyl‐propioimidate‐1‐^14^C hydrochloride, chlorination with Cl~2~ in NaOCl to produce methyl N‐chlorophenylpropioimidate‐1‐^14^ C, followed b