All o p t i c a l l y a c t i v e amino a c i d s were o f t h e L-configuration.
Synthesis of 14C and 3H labeled arabinosyl-5-azacytosine
β Scribed by George F. Taylor; Kahveh Zamani; John A. Kepler
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- French
- Weight
- 280 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
β¦ Synopsis
Arabi nosy1 -[6-3H] 5-azacytosi ne is prepared by catalytic exchange with tritium gas. The preparation o f arabinosyl-[2,4-14C]5azacytosine from barium [14C]carbonate via [U-14C]guanylurea and [2,4-14C]5-azacytosine is described.
π SIMILAR VOLUMES
A synthesis of dibucaine labeled with l"C in the heterocyclic ring is described. starting with isatin and acetic anh~dride-2-~"C as shown in Scheme I. Two deutero analogs, dibucaine-d2 and dibucaine-dg, were also synthesized by the reactions shown in Scheme 11. Dibucaine-dg was synthesized by conden
## Abstract The preparation of [^3^H]Sch 727965 from unlabeled compound and tritiated water was base catalyzed. Diethyl [^13^C~3~]malonate was used to prepare [^13^C~3~]Sch 727965 in five steps in 21.8% overall yield. In a similar manner, [^14^C]Sch 727965 was prepared in five steps from diethyl [2
3H-Sch 47949, racemic 3H-Sch 48461, was prepared at a specific activity of 40 mCi/mmole by Pt catalysed exchange with tritiated water. 3H-Sch 48461 was prepared at a specific activity of 64.6 Ci/mmole by a Pd/C catalysed reduction of an olefinic intermediate. 14C-Sch 48461 was prepared in 8 steps fr
## Abstract ^2^H and ^3^H labelled Sch 40120 were prepared by Pt catalysed exchange with isotopic water. D7βSch 40120 was obtained in two exchanges in 53% yield and ^3^HβSch 40120 was prepared by a single exchange at a specific activity of 19.8 Ci/mmole. ^14^CβSch 40120 was prepared in 4 steps from