Synthesis of 1,4-diketones in good yields was achieved by the coupling reaction of the trinethylsilyl enol ethers of acetophenone, thiophene or furan with lead tetraacetate in dry dichloromethane and tetrahydrofuran at -78"C.
โฆ LIBER โฆ
Synthesis of 1,4-diketones by oxidative coupling of kitone enolates and trimethylsilyl enol ethers with cupric trifluoromethanesulfonate
โ Scribed by Yoshiro Kobayashi; Takeo Taguchi; Etsuko Tokuno
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- French
- Weight
- 123 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0040-4039
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Synthesis of 1,4-Diketones: Unusual Coupling of Tin Enolates with ฮฑ-Chloro Ketones Catalyzed by Zinc Halides. -In the absence of zinc halides functionalized chlorohydrin derivatives such as (IV) are formed. -