Synthesis of 13C-labeled steroid hormones
โ Scribed by Gijsbert Zomer; Johannes F.C. Stavenuiter
- Book ID
- 116065458
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 289 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0039-128X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The syntheses of '%-ring labeled levamisole ([-)-2,3,5,6-tetrahydr0-6-phenyl[~'C-UL]imidazo(Z, 1b]thiole) from acetophenone-ring-UL-l'C in 5 steps plus resolution with a 7.5% overall yield, and %,-ring labeled tetramisole ([i]-2,3,5,6-tetrahydro-6-phenyif3 S ]imidaz0[2,?-bjthiazole) from benzene-'%,
Alkylation o f ethyl acetoacetate-13Cq with eth lene oxide and ethylene oxide-13C2 af Eorded 2-a~etylbutyrolactone-'~C~, (5) and the hexalabeled form (c), respectively. Treatment o f the lactone with an excess of 48% hydrobromic acid effected decarboxylation with bromide displacement t o yield 5-bro