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Synthesis of [11C]cyanamide, a versatile synthon for the production of 11C-labelled radiopharmaceuticals

✍ Scribed by Perry S. Kruijer; Peter J. van Leuffen; Jacobus D.M. Herscheid


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
387 KB
Volume
47
Category
Article
ISSN
0969-8043

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11C-Labelled radiopharmaceuticals: Synth
✍ H.-J. Machulla; K. Dutschka πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 French βš– 210 KB

Starting with "CO , [carboxyl-llC1-nicotinic acid amide was synthesized via 3-p$ridyl-lithium in practically carrierfree amounts within 60 minutes. Overall radiochemical yields between 20% and 30% were obtained. Identification and purification of the labelled product was carried out by high pressure