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11C-Labelled radiopharmaceuticals: Synthesis and high pressure liquid chromatography of nicotinic-11C acid amide

✍ Scribed by H.-J. Machulla; K. Dutschka

Publisher
John Wiley and Sons
Year
1979
Tongue
French
Weight
210 KB
Volume
16
Category
Article
ISSN
0022-2135

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✦ Synopsis

Starting with "CO , [carboxyl-llC1-nicotinic acid amide was synthesized via 3-p$ridyl-lithium in practically carrierfree amounts within 60 minutes. Overall radiochemical yields between 20% and 30% were obtained. Identification and purification of the labelled product was carried out by high pressure liquid chromatography using water as eluent.

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