๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of (1-substituted piperidin-4-yl)-1H-benzimidazoles and (1-substituted piperidin-4-yl)-3,4-dihydroquinazolines as possible antihypertensive agents

โœ Scribed by Hiroyuki Obase; Haruki Takai; Masayuki Teranishi; Nobuhiro Nakamizo


Book ID
112127090
Publisher
Journal of Heterocyclic Chemistry
Year
1983
Tongue
English
Weight
515 KB
Volume
20
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Syntheses of aza and fluorine-substitute
โœ Xiaojun Han; Rita L. Civiello; Stephen E. Mercer; John E. Macor; Gene M. Dubowch ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 178 KB

A practical and expedient synthesis of the title compounds is described. They were prepared by Stille reaction of nitro halopyridines 4 or nitro fluro-halobenzenes 10, followed by Michael addition of tertbutyl 4-aminopiperidine-1-carboxylate to the resulting activated vinyl compounds 5 and 11, hydro