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Synthesis of 1-methyl-4-(5-14C-3-methyl-5-isoxazolyl) pyridinium chloride

✍ Scribed by Victor J. Bauer; Anthony E. Lanzilotti

Publisher: John Wiley and Sons
Year: 1969
Tongue: French
Weight: 135 KB
Volume: 5
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2590050114

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✦ Synopsis

Synthesis of l-Methyl-4-(5-14C-3-methyl-5-isoxazolyl) pyridinium Chloride

Received on 21st November 1968 l-Methyl-4-(3-methyl-5-isoxazolyl)pyridinium chloride (1) has been found to display interesting hypoglycemic activity in laboratory animals, and is currently undergoing extensive evaluation as a potential antidiabetic drug. To facilitate the study of the bodily distribution and metabolism of 1, a radiolabelled sample was required.

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