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Synthesis of 2,6-dimethylbenzamide N-(5-methyl-3-isoxazolyl) (D2916) labelled with 14C

✍ Scribed by Elmostafa Azim; Jean Claude Maurizis; Jean Michel Dupuy; Françis Lepage; Annie Veyre; Jean Claude Madelmont


Publisher
John Wiley and Sons
Year
1997
Tongue
French
Weight
175 KB
Volume
39
Category
Article
ISSN
0022-2135

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Three selectively labeled propynes were prepared either with deuterium or carbon-13 at position 3 and doubly labeled with carbon-13 at positions 1 and 2 by an alkylation reaction from the corresponding labeled or unlabeled monolithio acetylides and dimethylsulfates. Their lithiation with nBuLi gave