𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and characterization of 2-hydroxymethyl-1-methyl-4-nitro-5-imidazolcarbonitrile-4, 5-14C

✍ Scribed by Robert L. Ellsworth; Henry T. Meriwether; Holly E. Mertel

Publisher
John Wiley and Sons
Year
1990
Tongue
French
Weight
306 KB
Volume
28
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Preparation of the title compound, a key intermediate required to assist in the investigation and development of a new class of substances for controlling coccidiosis, is described. This labeled substance was synthesized in 10 steps, with a 17% overall radiochemical yield, from oxalic‐1,2‐^14^C acid.

πŸ“œ SIMILAR VOLUMES

Synthesis of 1, 3-dihydro-1-methyl-7-nit
Synthesis of 1, 3-dihydro-1-methyl-7-nitro-5-phenyl-2H-1, 4-benzodiazepin-2-one-5-14c (nimetazepam-5-14C)
✍ A. Yoshitake; Y. Makari; M. Endo πŸ“‚ Article πŸ“… 1972 πŸ› John Wiley and Sons 🌐 French βš– 243 KB πŸ‘ 1 views

## Abstract The synthesis from carbon‐^14^C dioxide of 1, 3‐dihydro‐1‐methyl‐7‐nitro‐5‐phenyl‐2H‐1, 4‐benzodiazepin‐2‐one‐5‐^14^C (I) for use in metabolic studies has been described. The synthesis was achieved by the sequence shown in figure 1. The overall yield of labelled nimetazepam (I) was near

Synthesis of 3-cyano-4-methyl-5(14C)-met
Synthesis of 3-cyano-4-methyl-5(14C)-methyl-2-(5-14C)pyrrolyloxamic acid
✍ I. L. Honigberg; N. M. Meltzer; C. D. Blanton Jr. πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 French βš– 181 KB πŸ‘ 1 views

A synthesis of 3-cyano-4-methyl-5 ( 14 C)-methyl-2-(5-14C)pyrrolyloxamic acid is described. The compound, having specific activity of 66.7 pCi/mmole, was obtained in 19.68% overall yield from uniformly labelled 14C-l-alanine. 14 14 Key Words: 3-Cyano-4-methyl-5( C)-methyl-2-(5-C)pyrrolyloxamic acid,

Synthesis of 2-methyl-4(5)-nitro[15N1(3)
Synthesis of 2-methyl-4(5)-nitro[15N1(3)]imidazole from 2-methyl-4(5)-nitroimidazole
✍ Jerzy SuwiΕ„ski; Wojciech Szczepankiewicz πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 French βš– 330 KB πŸ‘ 1 views

A simple four-stage conversion of 2-1nethyl-4(5>nitroimidazole to 2-methyl-4(5)-nitr0['~N""]imidazole is reported. The method consists in N-nitration of the initial compound to ?-methyl-1,4-dinitroimidazole, treating the latter with ["Nlglycine and N-dealkylation of the obtained (~-rnethyl-4-nitro[~

Synthesis of 1-methyl-4-(5-14C-3-methyl-
Synthesis of 1-methyl-4-(5-14C-3-methyl-5-isoxazolyl) pyridinium chloride
✍ Victor J. Bauer; Anthony E. Lanzilotti πŸ“‚ Article πŸ“… 1969 πŸ› John Wiley and Sons 🌐 French βš– 135 KB πŸ‘ 1 views

## Synthesis of l-Methyl-4-(5-14C-3-methyl-5-isoxazolyl) pyridinium Chloride Received on 21st November 1968 l-Methyl-4-(3-methyl-5-isoxazolyl)pyridinium chloride (1) has been found to display interesting hypoglycemic activity in laboratory animals, and is currently undergoing extensive evaluation