✦ LIBER ✦

Synthesis of 1-[4-[3-(N-methyl N-[3,4-dimethoxy β-phenethyl]amino] [3-14C]propyloxy] benzenesulfonyl]-2-isopropyl indolizine or [14C]SR 33557

✍ Scribed by R. Demotte; M. Deblaton; M. Winand; M. Callaert; R. Sion; J. Gubin; P. Chatelain

Publisher: John Wiley and Sons
Year: 1990
Tongue: French
Weight: 184 KB
Volume: 28
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580281005

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

[^14^C]SR 33557 was synthesized in six steps and in an overall yield of 3.8% from sodium [^14^C]cyanide.

📜 SIMILAR VOLUMES

Synthesis of [2-14C] fantofarone or 1-[4

Synthesis of [2-14C] fantofarone or 1-[4-[3-N-methyl N-[3,4-dimethyl β-phenethyl] amino propyloxy] benzene sulfonyl]-2-isopropyl [2-14C] indolizine

✍ P. Pointeau; Y. Berger 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 303 KB

## Abstract Sodium [1‐^14^C] isobutyrate: 1 was obtained by carbonation of isopropyl magnesium bromide with ^14^CO~2~. From: 1 [1‐^14^C] isobutyryl chloride: 3 was prepared, which through the successive actions of diazomethane and hydrogen bromide gave rise to 1‐bromo 3 methyl [2‐^14^C] 2‐butanone:

Synthesis of 1-14C-(1S, 4S)-N-methyl-4-(

Synthesis of 1-14C-(1S, 4S)-N-methyl-4-(3,4-dichlophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine L-mandelate (1-14C-sertraline mandelate)

✍ Willard M. Welch; Dawn M. Viveiros 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 300 KB

Synthesis of N-(2,3-dihydro-1-[14C]methy

Synthesis of N-(2,3-dihydro-1-[14C]methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-benzamide and N-(2,3-dihydro-1-[14C]methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N-[14C]methyl-benzamide as novel carbon-14 labelled CCK antagonists

✍ Hojatollah Matloubi; Ali Khalaj; Reza Dowlatabadi; Gholamhossein Shirvani 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 74 KB

## Abstract Two benzodiazepine CCK antagonists __N__‐(2,3‐dihydro‐1‐[^14^C]methyl‐2‐oxo‐5‐phenyl‐1H 1,4‐benzodiazepin‐3‐yl)‐benzamide **2** and __N__‐(2,3‐dihydro‐1‐[^14^C]methyl‐2‐oxo‐5‐phenyl‐1H‐1,4‐benzodiazepin‐3‐yl)‐[^14^C]methyl‐benzamide **3** were synthesized in high yields through the reac

Synthesis of (S)-N-(endo -8-methyl-8-aza

Synthesis of (S)-N-(endo -8-methyl-8-azabicyclo[3.2.1] oct-3α-yl)-4-amino-5-chloro-2-(1-methyl-2-butynyloxy) [carbonyl-14C]benzamide monohydrochloride (14C-E3620)

✍ Yorihisa Hoshino; Shuhei Miyazawa; Hiroshi Nakata; Hironori Etoh; Mitsuko Furits 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 276 KB 👁 1 views

Synthesis of the anti-tumor agent CI-973

Synthesis of the anti-tumor agent CI-973 {[SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato(2)](2-methyl-1,4-[4-14C]butanediamine-N,N′)platinum}

✍ I. Victor Ekhato; James D. Hoeschele; Che C. Huang; Bela Nanavaty; Helen T. Lee 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 307 KB

## Abstract Starting from the chiral compound 1, (R)‐(+)‐2‐methyl‐1,4‐[^14^C]butanediamine 7 was synthesized in a sequence of reactions in which ^14^C‐label was introduce using label potassium cyanide. Compound 7 was reacted with potassium tetraiodoplatinate and silver 1,1‐cyclobutanedicarboxylate

Synthesis of 13C, 14C and 2H13C labeled

Synthesis of 13C, 14C and 2H13C labeled adrenoceptor antagonists: 6-chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepine hydrochloride and its N-desmethyl analog

✍ A. J. Villani; F. Etzkorn; G. A. Rotert; J. R. Heys 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 French ⚖ 428 KB

The compound 6-chloro-2,3,4,5-tetrahydroi~-methyl-l &3-t#nzazepine (SK&F 86466) was prepared in phenyl-U-C and phenyl-C , labeled forms in a six step sequence beginning with the appropriately labeled benzenes. In addition, the N-desmeJhyl analog of the carbon-1 4 labeled isotopomer and the N-methyl-