## Abstract ^99m^Tc‐CO‐MIBI was prepared by a two‐step procedure involving the convenient preparation of the [^99m^Tc(CO)~3~(OH~2~)~3~]^+^ precursor and followed by the substitution of the water molecules by the MIBI (2‐methoxyisobutylisonitrile) ligands. In a second step, the reaction solution was
Synthesis, characterization and biodistribution of 99mTc(CO)3–ABP and comparison with 99mTc–ABP
✍ Scribed by Jian Liu; Fenglong Wang; Junbo Zhang; Shuye Yang; Haixun Guo; Xuebin Wang
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- French
- Weight
- 110 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The organometallic precursor fac-[ 99m Tc(OH 2 ) 3 (CO) 3 ] + was reacted with trimethyl-bromoacetanilido-iminodiacetic acid (mebrofenin) in phosphate buffered saline (pH 7) at 708C for 1 h to produce the complex, 99m Tc(CO) 3mebrofenin, in >95% yields. High performance liquid chromatography analysi
## Abstract The preparation of complex ^99m^TcN–MIBI was carried out using two alternative procedures that led to the formation of the complex with high radiochemical purity (>90%). The partition coefficient, electrophoresis and cationic resin exchange experiments showed that the ^99m^TcN–MIBI is a
We evaluated lipophilicity and biodistribution of a series of 99m Tc(CO) 3 -ether isonitrile complexes to determine whether different lipophilicity and structure of isonitrile ligands would improve the imaging properties of the radiopharmaceutical for the heart. Novel 99m Tc(CO) 3 -MIBI analogs were