Preparation and biodistribution of complexes of 99mTc with thiol - oxime diligands
β Scribed by P. Adriaens; M. Remy; E. Vanbeselaere; G. Bormans; M. De Roo; A. Verbruggen
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- French
- Weight
- 111 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ^99m^TcβCOβMIBI was prepared by a twoβstep procedure involving the convenient preparation of the [^99m^Tc(CO)~3~(OH~2~)~3~]^+^ precursor and followed by the substitution of the water molecules by the MIBI (2βmethoxyisobutylisonitrile) ligands. In a second step, the reaction solution was
We evaluated lipophilicity and biodistribution of a series of 99m Tc(CO) 3 -ether isonitrile complexes to determine whether different lipophilicity and structure of isonitrile ligands would improve the imaging properties of the radiopharmaceutical for the heart. Novel 99m Tc(CO) 3 -MIBI analogs were