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SYNTHESIS, BIOLOGICAL ACTIVITY, AND TRITIATION OF L-3, 4-DEHYDROPROLINE-CONTAINING PEPTIDES

✍ Scribed by Felix, Arthur M. ;Wang, Ching-Tso ;Liebman, Arnold A. ;Delaney, Charles M. ;Mowles, Thomas ;Burghardt, Barbara A. ;Charnecki, Annette M. ;Meienhofer, Johannes

Book ID
115097318
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
784 KB
Volume
10
Category
Article
ISSN
0367-8377

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## Abstract Two tris‐alkoxycarbonyl homoarginine derivatives, Boc‐Har{Ο‰,ω′‐[Z(2Br)]~2~}‐OH and Boc‐Har{Ο‰,ω′‐[Z(2Cl)]~2~}‐OH, were prepared by guanidinylation of Boc‐Lys‐OH, and used for the synthesis of neo‐endorphins and dynorphins. The results were compared with that obtained in the synthesis in