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l-3,4-Dehydroproline analogs of bradykinin: Synthesis, biological activity, and solution conformation

โœ Scribed by George H. Fisher; David I. Marlborough; James W. Ryan; Arthur M. Felix


Book ID
115703629
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
465 KB
Volume
189
Category
Article
ISSN
0003-9861

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## Abstract The conformational study of __N__โ€acetylโ€__N__โ€ฒโ€methylamide of Lโ€3,4โ€dehydroproline (Acโ€Dhpโ€NHMe, the Dhp dipeptide) is carried out using hybrid density functional methods with the selfโ€consistent reaction field method in the gas phase and in solution (chloroform and water). The incorpo