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Synthesis applications of cationic aza-Cope rearrangements. 16. Stereocontrolled synthesis of substituted cis-cyclopenta[b]pyrrolidines

โœ Scribed by Overman, Larry E.; Okazaki, Mark E.; Jacobsen, E. Jon


Book ID
126972209
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
413 KB
Volume
50
Category
Article
ISSN
0022-3263

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Synthesis applications of aza-cope rearr
โœ Larry E Overman; E.Jon Jacobsen ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 226 KB

pyrroles can be prepared in stereocontrolled fashions by the reaction of 2-amino-l-(l-phenylvlnyl)cyclohexanols with formaldehyde and acid. Recent papers from our laboratory have described the use of "Mannich-directed" cationic aza-Cope rearrangements for the preparation of octahydroindolones by an