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Synthesis applications of cationic aza-Cope rearrangements. 20. Total synthesis of (.+-.)-meloscine and (.+-.)-epimeloscine

✍ Scribed by Overman, Larry E.; Robertson, Graeme M.; Robichaud, Albert J.


Book ID
125857479
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
380 KB
Volume
54
Category
Article
ISSN
0022-3263

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Synthesis applications of aza-cope rearr
✍ Larry E Overman; E.Jon Jacobsen πŸ“‚ Article πŸ“… 1982 πŸ› Elsevier Science 🌐 French βš– 226 KB

pyrroles can be prepared in stereocontrolled fashions by the reaction of 2-amino-l-(l-phenylvlnyl)cyclohexanols with formaldehyde and acid. Recent papers from our laboratory have described the use of "Mannich-directed" cationic aza-Cope rearrangements for the preparation of octahydroindolones by an