Synthesis and study of the anti-inflammatory properties of some pyrazolo[1,5-a]pyrimidine derivatives
β Scribed by Fabrizio Bruni; Annarella Costanzo; Silvia Selleri; Gabriella Guerrini; Roberto Fantozzi; Renato Pirisino; Sandra Brunelleschi
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 804 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0022-3549
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## Abstract magnified image A series of pyrazolopyrimidine and pyrazoloquinozoline derivatives has been synthesized in one step by multicomponent reactions using, 5βaminopyrazole, __pβ__substitutedbenzoylacetonitrile/dimedone and triethylorthoesters. pyrazolopyrimidine derivatives were also studie
Thiazolylcyanothioacetanilides react with β£-haloketones and haloesters to give the corresponding thiophene or thiazole derivatives according to the reaction conditions. Pyrazolo [1,5-a]pyrimidines and pyrazolo [5,1-c]triazines were synthesized by reaction of 3-amino-4-(4Π-arylthiazol-2Π-yl)-5-phenyl