Synthesis and purification of 11C-carboxyl-labeled amino acids
✍ Scribed by R.L. Hayes; L.C. Washburn; B.W. Wieland; T.T. Sun; J.B. Anon; T.A. Butler; A.P. Callahan
- Publisher
- Elsevier Science
- Year
- 1978
- Weight
- 176 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0020-708X
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## Abstract Ring‐opening of __N__‐(__tert__‐butoxycarbonyl)aziridine‐2‐isopropyl carboxylate with no‐carrier‐added (n.c.a.) [^11^C]cyanide is reported. Following purification by HPLC, the protected D,L‐[4‐^11^C]__β__‐cyanoalanine was subsequently hydrolysed, to yield D,L‐[4‐^11^C]asparagine or D,L‐