𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase

✍ Scribed by Sara Van Poecke; Hélène Munier-Lehmann; Olivier Helynck; Matheus Froeyen; Serge Van Calenbergh


Book ID
113495524
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
556 KB
Volume
19
Category
Article
ISSN
0968-0896

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Mycobacterium tuberculosis Thymidine Mon
✍ Philippe Van Rompaey; Koen Nauwelaerts; Veerle Vanheusden; Jef Rozenski; Hélène 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 170 KB

## Abstract __Mycobacterium tuberculosis__ thymidine monophosphate kinase (TMPKmt) has recently been introduced as a potential target for the structure‐based design of anti‐tuberculosis drugs. Based on the TMPKmt X‐ray structure and previous S.A.R. studies, we synthesised the nucleoside analogues *