Design of Mycobacterium tuberculosis Thymidine Monophosphate Kinase Inhibitors
β Scribed by H. Munier-Lehmann; S. Pochet; L. Dugue; O. Dutruel; G. Labesse; D. Douget
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 52 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract __Mycobacterium tuberculosis__ thymidine monophosphate kinase (TMPKmt) has recently been introduced as a potential target for the structureβbased design of antiβtuberculosis drugs. Based on the TMPKmt Xβray structure and previous S.A.R. studies, we synthesised the nucleoside analogues *
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