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ChemInform Abstract: A New Family of Inhibitors of Mycobacterium tuberculosis Thymidine Monophosphate Kinase.

✍ Scribed by C. Gasse; V. Huteau; D. Douguet; H. Munier-Lehmann; S. Pochet

Publisher: John Wiley and Sons
Year: 2008
Weight: 15 KB
Volume: 39
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200812248

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## Abstract __Mycobacterium tuberculosis__ thymidine monophosphate kinase (TMPKmt) has recently been introduced as a potential target for the structure‐based design of anti‐tuberculosis drugs. Based on the TMPKmt X‐ray structure and previous S.A.R. studies, we synthesised the nucleoside analogues *

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