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Synthesis and in vitro evaluation of the anticancer activity of novel fluorinated thiazolo[4, 5-d]pyrimidines

โœ Scribed by Hesham T. Y. Fahmy; Sherif A. F. Rostom; Manal N. Saudi; Jordan K. Zjawiony; David J. Robins


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
170 KB
Volume
336
Category
Article
ISSN
0365-6233

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โœ Hai-Bo Shi; Hai-Bo Li; Kong-Qin Lu; Xia-Re Zhu; Wei-Xiao Hu; Wen Pei ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 150 KB ๐Ÿ‘ 1 views

## Abstract A series of novel compounds **7โ€“43** were prepared __via__ the condensation of enaminones **4aโ€“h** and the guanidines carbonate **6aโ€“f**. The structures of these newly synthesized compounds were confirmed by ^1^Hโ€NMR, MS, EA and IR. All the compounds were tested for their cytotoxic acti