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Synthesis and In Vitro Antibacterial Evaluation of Novel Imidazo[2′, 1′:5, 1]-1, 2, 4-triazolo[4, 3-c]-quinazoline Derivatives of 5-Thioxo-1, 2, 4-triazole, 4-Oxothiazolidine, and their Open-chain Counterparts

✍ Scribed by Magda N. Nasr; Magdy M. Gineinah; Eman R. El-Bendary


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
96 KB
Volume
336
Category
Article
ISSN
0365-6233

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With sodium borohydride in tetrahydrofuran/ethanol (5 : 1). the product ( I ) gives a 75 yield of a compound, m.p. 233 "C, that is identical with the recently prepared 2-(diphenylmethyl)imidaz0le[~1. When product ( I ) is boiled for 2 h in tetrahydrofuran/water (2: I ) it affords 2-(hydroxy-dipheny