Synthesis and Antitumor Evaluation of New Polysubstituted Thiazole and Derived Thiazolo[4, 5-d]pyrimidine Systems
β Scribed by Hesham T. Y. Fahmy; Sherif A. F. Rostom; Adnan A. Bekhit
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 147 KB
- Volume
- 335
- Category
- Article
- ISSN
- 0365-6233
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Several ethyl 2, pyridine-2-alkanoate derivatives were synthesized as herbicides. Only 5-methyl derivatives inhibited both hypocotyl and root growth in the lettuce (L actuca sativa L.) seedling test at 100 mg litre~1. Only ethyl propionate and valerate derivatives showed signiΓcant inhibition at 0Γ
## Abstract Derivatives **7**β**13** of a new tricyclic heteroaromatic system, pyrido[3β²,2β²:5,6]thiopyrano[4,3β__c__]pyridazinβ3(2__H__,5__H__)βone, were prepared as potential ligands at the benzodiazepine receptor, in view of their structural analogy with potent ligands such as the pyrazoloquinoli