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Synthesis and Antitumor Evaluation of New Polysubstituted Thiazole and Derived Thiazolo[4, 5-d]pyrimidine Systems

✍ Scribed by Hesham T. Y. Fahmy; Sherif A. F. Rostom; Adnan A. Bekhit


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
147 KB
Volume
335
Category
Article
ISSN
0365-6233

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## Abstract Derivatives **7**–**13** of a new tricyclic heteroaromatic system, pyrido[3β€²,2β€²:5,6]thiopyrano[4,3‐__c__]pyridazin‐3(2__H__,5__H__)‐one, were prepared as potential ligands at the benzodiazepine receptor, in view of their structural analogy with potent ligands such as the pyrazoloquinoli