✦ LIBER ✦

Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens

✍ Scribed by Li, Xun; Singh, Shankar M.; Cote, Jean; Laplante, Sylvie; Veilleux, Raymonde; Labrie, Fernand

Book ID: 127191213
Publisher: American Chemical Society
Year: 1995
Tongue: English
Weight: 824 KB
Volume: 38
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00009a006

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Vinyl fluoride as a mimic of the ‘interm

Vinyl fluoride as a mimic of the ‘intermediate’ enol form in the 5α-reductase transformation: Synthesis and in vitro activity of (N-1′,1′-Dimethylethyl)-3-haloandrost-3,5-diene-17β-carboxamides

✍ Xun Li; Shankar M. Singh; Van Luu-The; Jean Côté; Sylvie Laplante; Fernand Labri 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 466 KB

Synthesis and in vitro antiandrogenic ac

Synthesis and in vitro antiandrogenic activity of 17β-hydroxy-17α-(ω-hydroxy/haloalkyn-1′-yl)-4-methyl-4-aza-3-oxo-5α-androstan-(1-ene)-3-ones

✍ Xun Li; Shankar M. Singh; Mettilda Lourdusamy; Yves Mérand; Raymonde Veilleux; F 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 208 KB

Synthesis and in vitro Evaluation of 1,2

Synthesis and in vitro Evaluation of 1,2,4-Triazolo[1,5- a ][1,3,5]triazine Derivatives as Thymidine Phosphorylase Inhibitors

✍ Bera, Hriday; Dolzhenko, Anton V.; Sun, Lingyi; Dutta Gupta, Sayan; Chui, Wai-Ke 📂 Article 📅 2013 🏛 John Wiley and Sons 🌐 English ⚖ 914 KB

Radiolabeling and in vitro / in vivo eva

Radiolabeling and in vitro / in vivo evaluation of N-(1-adamantyl)-8-methoxy-4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxamide as a PET probe for imaging cannabinoid type 2 receptor

✍ Mu, Linjing; Bieri, Daniel; Slavik, Roger; Drandarov, Konstantin; Müller, Adrien 📂 Article 📅 2013 🏛 John Wiley and Sons 🌐 English ⚖ 743 KB

Synthesis and Biological Evaluation of 2

Synthesis and Biological Evaluation of 2′-Oxo-2,3-dihydro-3′H- spiro[chromene-4,5′-[1,3]oxazolidin]-3′yl]acetic Acid Derivatives as Aldose Reductase Inhibitors

✍ Simona Rapposelli; Federico Da Settimo; Maria Digiacomo; Concettina La Motta; An 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB 👁 1 views

ChemInform Abstract: Synthesis and Biolo

ChemInform Abstract: Synthesis and Biological Evaluation of [2′-Oxo-2,3-dihydro-3′H-spiro[chromene-4,5′- [1,3]oxazolidin]-3′yl]acetic Acid Derivatives as Aldose Reductase Inhibitors.

✍ Simona Rapposelli; Frederico Da Settimo; Maria Digiacomo; Concettina La Motta; A 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 62 KB 👁 1 views

## Abstract A series of the title spirocyclic benzopyran derivatives (XI) (12 examples) is synthesized, which all prove to be selective inhibitors of aldose reductase (ARL2).