Synthesis and hypoglycemic activity of phenacyltriphenylphosphoranes and phosphonium salts
โ Scribed by Blank, Benjamin; DiTullio, Nicholas W.; Deviney, Linda; Roberts, John T.; Saunders, Harry L.
- Book ID
- 125832458
- Publisher
- American Chemical Society
- Year
- 1975
- Tongue
- English
- Weight
- 330 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-2623
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๐ SIMILAR VOLUMES
A short and efficient synthesis of the two enantiomeric iron-complcxed phosphonium salts (+)-1 and (-)-2 is described. Upon reaction with the chiral fotmyloxirane 3, the corresponding chiral ylides exhibit quite difietent mactivities. Few examples of Wittig-type reactions with phosphotus or sulphur
In CC14 solution the singlet signal for the hydroxymethyl group is at T = 6.68 (3 H), but in dimethyl sulfoxide there arc two signals with relative areas 1:2 (OH;CH2). The signal for the vinyl protons occurs at T = 5.42 (2 H). Infrared spectrum: 880, 1640, 1770, 3070 (=CH2), 1035, 3360 (broad associ