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Synthesis and hybridization studies of α-configured arabino nucleic acids

✍ Scribed by Gupta, Pankaj; Maity, Jyotirmoy; Shakya, Gaurav; Prasad, Ashok K.; Parmar, Virinder S.; Wengel, Jesper


Book ID
118272474
Publisher
Royal Society of Chemistry
Year
2009
Tongue
English
Weight
257 KB
Volume
7
Category
Article
ISSN
1477-0520

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α-LNA (Locked Nucleic Acid with α-D-Conf
✍ Poul Nielsen; Nanna K. Christensen; Jakob K. Dalskov 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB 👁 1 views

Alpha-LNA is presented as a stereoisomer of LNA (locked nucleic acid) with alpha-D-configuration. Three different approaches towards the thymine alpha-LNA monomer as well as the 5-methylcytosine alpha-LNA monomer are presented. Different alpha-LNA sequences have been synthesised and their hybridisat