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Bis-Pyrene-Modified Unlocked Nucleic Acids: Synthesis, Hybridization Studies, and Fluorescent Properties

✍ Scribed by Perlíková, Pavla; Ejlersen, Maria; Langkjaer, Niels; Wengel, Jesper


Book ID
127133242
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
625 KB
Volume
9
Category
Article
ISSN
1860-7179

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Pyrene-Modified Unlocked Nucleic Acids:
✍ Dr. Kasper K. Karlsen; Dr. Anna Pasternak; Dr. Troels B. Jensen; Prof. Dr. Jespe 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 988 KB

## Abstract Two pyrene‐modified UNA monomers were synthesized and incorporated into 21‐mer DNA oligonucleotides. Melting temperatures and thermodynamic properties of the modified duplexes were measured, and the fluorescence properties of single strands and duplexes containing one or more pyrene‐UNA