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Synthesis and Fluorogenic Properties of Some 1-(Coumarin-7-yl)-4,5-dihydro-1,2,4-triazin-6(1H)-ones

โœ Scribed by Mustafa, Mohammad S; El-Abadelah, Mustafa M; Mubarak, Mohammad S; Chibueze, Ihekwereme; Shao, Di; Agu, Remigius U


Book ID
118019115
Publisher
Canadian Center of Science and Education
Year
2011
Weight
897 KB
Volume
3
Category
Article
ISSN
1916-9698

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Efficient solid-phase synthesis of 4,5-d
โœ Damien Boeglin; Sonia Cantel; Jean Martinez; Jean-Alain Fehrentz ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 121 KB

A new and easy protocol for the formation of substituted 4,5-dihydro-1,2,4-triazin-6(1H)-ones was developed on solid support. The heterocyclic compounds were formed by nucleophilic reaction of hydrazine on thioamide esters. As cyclization was concomitant with cleavage from the support, substituted 4