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Dihydro-1,2,4-triazin-6(1H)-ones. II Synthesis of Several Methylated 3-Phenyl- 4,5-dihydro-1,2,4-triazin-6(1H)-ones

✍ Scribed by Collins, David J.; Hughes, Timothy C.; Johnson, Wynona M.


Book ID
115493395
Publisher
Commonwealth Scientific and Industrial Research Organisation Publishing
Year
1999
Tongue
English
Weight
201 KB
Volume
52
Category
Article
ISSN
0004-9425

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Efficient solid-phase synthesis of 4,5-d
✍ Damien Boeglin; Sonia Cantel; Jean Martinez; Jean-Alain Fehrentz πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 121 KB

A new and easy protocol for the formation of substituted 4,5-dihydro-1,2,4-triazin-6(1H)-ones was developed on solid support. The heterocyclic compounds were formed by nucleophilic reaction of hydrazine on thioamide esters. As cyclization was concomitant with cleavage from the support, substituted 4