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Synthesis and Evaluation of N , N -Dialkyl Enkephalin-Based Affinity Labels for δ Opioid Receptors

✍ Scribed by Maeda, Dean Y.; Ishmael, Jane E.; Murray, Thomas F.; Aldrich, Jane V.


Book ID
125941469
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
99 KB
Volume
43
Category
Article
ISSN
0022-2623

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Synthesis and evaluation of derivatives
✍ Heekyung Choi; Thomas F. Murray; Jane V. Aldrich 📂 Article 📅 2003 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 82 KB

As part of an effort to develop peptide-based affinity labels for opioid receptors, [Leu(5)]enkephalin (LeuEnk) and DTLET (Tyr-D-Thr-Gly-Phe-Leu-Thr), potent agonists for delta receptors, were selected as the parent peptides for further modification. The affinity label derivatives were prepared usin