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Synthesis and Biological Evaluation of N-Substituted Quinolinimides, as Potential Ligands for in Vivo Imaging Studies of δ-Opioid Receptors

✍ Scribed by Bourdier, Thomas; Poisnel, Géraldine; Dhilly, Martine; Delamare, Jérôme; Henry, Joël; Debruyne, Danièle; Barré, Louisa


Book ID
126328873
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
281 KB
Volume
18
Category
Article
ISSN
1043-1802

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✍ Ursula Scheffel; John R. Lever; Philip Abraham; Karol R. Parham; William B. Math 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 80 KB 👁 1 views

Variously substituted phenyltropanes are proven as superb binding ligands for the dopamine transporter (DAT). In this study, we examine four N-substituted phenyltropanes which are derivatives of RTI-55 as in vivo binding ligands in mice. In this series, the methyl group on the nitrogen was replaced