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Synthesis of enkephalin-based affinity labels for delta opioid receptors

✍ Scribed by DY Maeda; TF Murray; JE Roth; JV Aldrich


Book ID
119118625
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
114 KB
Volume
54
Category
Article
ISSN
0167-0115

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As part of an effort to develop peptide-based affinity labels for opioid receptors, [Leu(5)]enkephalin (LeuEnk) and DTLET (Tyr-D-Thr-Gly-Phe-Leu-Thr), potent agonists for delta receptors, were selected as the parent peptides for further modification. The affinity label derivatives were prepared usin