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Affinity Labeling of δ Opioid Receptors by an Enkephalin-Derivative Alkylating Agent, DSLET-Mal

✍ Scribed by Ildikó Szatmári; György Orosz; Kálmán Medzihradszky; Anna Borsodi


Book ID
115584778
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
89 KB
Volume
265
Category
Article
ISSN
0006-291X

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As part of an effort to develop peptide-based affinity labels for opioid receptors, [Leu(5)]enkephalin (LeuEnk) and DTLET (Tyr-D-Thr-Gly-Phe-Leu-Thr), potent agonists for delta receptors, were selected as the parent peptides for further modification. The affinity label derivatives were prepared usin