๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis and evaluation of 5-aminosalicyl-glycine as a potential colon-specific prodrug of 5-aminosalicylic acid

โœ Scribed by Yun Jin Jung; Jeoung Soo Lee; Hak Hyun Kim; Young Mi Kim; Suk Kyu Han

Book ID
105671676
Publisher
Springer
Year
1998
Tongue
English
Weight
469 KB
Volume
21
Category
Article
ISSN
0253-6269

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Colon-specific prodrugs of 5-aminosalicy
Colon-specific prodrugs of 5-aminosalicylic acid: Synthesis and in vitro/in vivo properties of acidic amino acid derivatives of 5-aminosalicylic acid
โœ Yun Jin Jung; Jeoung Soo Lee; Young Mi Kim ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 159 KB ๐Ÿ‘ 1 views

5-Aminosalicyl-L-aspartic acid (5-ASA-Asp) and 5-aminosalicyl-L-glutamic acid (5-ASA-Glu) were synthesized and their properties as colon-speciยฎc prodrugs of 5aminosalicylic acid (5-ASA) were investigated employing rats as test animals. Incubation of 5-ASA-Asp and 5-ASA-Glu with the homogenates of ti

N,Nโ€ฒ-Bis(5-aminosalicyl)-L-cystine is a
N,Nโ€ฒ-Bis(5-aminosalicyl)-L-cystine is a potential colon-specific 5-aminosalicylic acid prodrug with dual therapeutic effects in experimental colitis
โœ Heejung Kim; Jeongsoon Huh; Hyunchu Jeon; Daekyu Choi; Jungoh Han; Youngmi Kim; ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 215 KB

To evaluate N,N 0 -bis(5-aminosalicyl)-L-cystine (5-ASA-Cys) as a potential colon-specific 5-aminosalicylic acid prodrug with dual therapeutic effects in experimental colitis, the pharmacokinetics and therapeutic activity were investigated after oral administration of 5-ASA-Cys and amelioration of e