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Synthesis and enzymatic resolution of DL-2-phenylglycine-1-14C

✍ Scribed by Ruth Billings; Hugh R. Sullivan

Publisher
John Wiley and Sons
Year
1967
Tongue
French
Weight
181 KB
Volume
3
Category
Article
ISSN
0022-2135

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✦ Synopsis

DL-2-Phenylglycine-I-14C was prepared in good yield employing a modified Strecker synthesis. The resolution of DL-2-phenylglycine into its pure enantiomorphs was accomplished by the stereoselective enzymatic hydrolysis of the N-chloroacetyl derivative of the Loptical isomer using hog kidney acylase.

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