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Synthesis and biological evaluation of ester prodrugs of benzafibrate as orally active hypolipidemic agents

✍ Scribed by Bandgar, Babasaheb P.; Sarangdhar, Rajendra J.; Fruthous, Khan; Mookkan, Jeyamurugan; Chaudhary, Shilpee; Chavan, Hemant V.; Bandgar, Sunil B.; Kshirsagar, Vinayak Y.

Book ID
119234102
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
358 KB
Volume
57
Category
Article
ISSN
0223-5234

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## Abstract In order to evaluate the anti‐hyperlipidemic effect of synthetic chalcones and some analogues, nineteen compounds with different substituents in both rings were synthesized and hypolipidemic activities were measured __in vivo__ using Triton WR1339 acute and hypercaloric chronic assays.