Synthesis and biological evaluation of a
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Satish K. Chitneni; Tom De Ruymaeker; Jan Balzarini; Alfons M. Verbruggen; Guy M
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Article
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2007
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John Wiley and Sons
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French
⚖ 125 KB
## Abstract The synthesis and preliminary biological evaluation of a lipophilic, fluorine‐18‐labeled 5‐ethynyl‐2′‐deoxyuridine derivative [^18^F]‐**3** is described. Initially, 5‐ethynyl‐2′‐deoxyuridine **5** was synthesized by coupling trimethylsilyl protected acetylene to 5‐iodo‐2′‐deoxyuridine *