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Synthesis and Biological Characterization of (3R,4R)-4-(2-(Benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and Its Stereoisomers for Activity toward Monoamine Transporters

✍ Scribed by Prashant S. Kharkar; Angela M. Batman; Juan Zhen; Patrick M. Beardsley; Maarten E. A. Reith; Aloke K. Dutta


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
346 KB
Volume
4
Category
Article
ISSN
1860-7179

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Di-n-butyl-, triphenyl and tri-n-butyltin derivatives of 3S,4S-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl-4-[(R)-1-carboxyethyl]-2-azetidinone were synthesized and characterized. Their antitumour activity was screened against seven tumoural cell lines of human origin. Copyright