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Di- and tri-organotin derivatives of 3S,4S-3-[(R)-1-(tert-butyl-dimethylsilyloxy)ethyl]-4-[(R)-1-carboxyethyl]-2-azetidinone: synthesis, characterization and in vitro antitumour activity

✍ Scribed by Marcel Gielen; Hassan Dalil; Monique Biesemans; Bernard Mahieu; Dick de Vos; Rudolph Willem

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 60 KB
Volume: 13
Category: Article
ISSN: 0268-2605
DOI: 10.1002/(sici)1099-0739(199907)13:7<515::aid-aoc875>3.0.co;2-b

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✦ Synopsis

Di-n-butyl-, triphenyl and tri-n-butyltin derivatives of 3S,4S-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl-4-[(R)-1-carboxyethyl]-2-azetidinone were synthesized and characterized. Their antitumour activity was screened against seven tumoural cell lines of human origin. Copyright

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